THC Removal – Remove THC from CBD | B/R Instrument Blog | Industry Leader in Laboratory Distillation Equipment How to extract CBD oil – The extraction process & how to make CBD oil CBD (Cannabidiol) is a compound that has shown promise in a variety of medical applications, like relief from pain and British pharmaceutical company GW Pharmaceuticals recently received FDA approval of their oral solution Epidolex for treating seizures associated with
THC Removal – Remove THC from CBD
Consumers are attracted to the purported health benefits of CBD but understand that THC naturally occurs in hemp along with other minor cannabinoids. They do not want to consume THC because they don’t want the “high” the comes along with THC or they don’t want to possibly test positive for THC in a work drug screening. The good news is that THC can be separated from CBD so that it can be consumed without concern for unwanted THC.
There are several ways to remove THC from CBD oil, CBD extracts and CBD distillate. The products can be THC Free (T Free) or low THC (0.3% or lower) which does not produce a “high”.
Broad Spectrum CBD
Broad spectrum products contain all of the cannabinoids with little THC (less than 0.3%/wt). This should not to be confused with THC Free or T-Free oil which contains no THC.
Chromatographic methods such as flash chromatography and CPC use solvents and a stationary phase to fractionate the cannabinoids from one another. In these processes, the THC is isolated and removed from the other cannabinoids. But, there is the unwanted side effect of losing some or all of the minor cannabinoids and CBD in the THC fraction.
In addition to using large volumes of solvents, chromatographic methods remove THC at a fairly slow rate and some CBD is lost in the process. At the same time, it requires an experienced operator to be available at all times during operation.
SCB-15 THC Remediation System
SCB-15 – Solvent Free THC Remediation System
Another technique for removing THC from full spectrum CBD is the SBC solvent free remediation system. This THC removal process is solvent free. It uses automation to maintain the optimum vacuum, temperature, and other parameters to remove THC (and some CBD) from the CBD oil. An operator occasionally monitors the THC level by Near Infrared or HPLC. Up to 100 liters of CBD or CBG oil can be remediated in 12-24 hours.
Pure CBD (also called isolate) can be produced by crystallizing CBD oil/extract/distillate. CBD oil is mixed with pentane and cooled until the CBD crystallizes (crashes out). Crystallized CBD is filtered, rinsed, and dried. Purities of 99+% are possible. Re-crystallization can increase the purity even higher. All THC is removed along with minor cannabinoids.
CBD Crystals or “Isolate”
Full spectrum CBD
The “entourage effect” is the name given to the synergistic benefits of cannabinoids and terpenes working together in your body. It has been the subject of study for many years, however we are still only beginning to understand some of the possibilities. The entourage effect can produce many different results depending on the combinations.
Full spectrum is a term that applies to extracts or oils that contain all of the naturally occurring cannabinoids from the plant. For hemp products this often includes more than 0.3% THC. In order to stay legally compliant, something must remove the THC.
this is what i want to start doing as my income resource i want to learn everything i can about how this is done and if i need to attend a class or school to get the right training if you would please send me some information on what i should be doing in order to start the process would really be great thanks very much for your time ———————————- scott
How to extract CBD oil – The extraction process & how to make CBD oil
CBD (Cannabidiol) is a compound that has shown promise in a variety of medical applications, like relief from pain and anxiety which are most common, along with many other ailments. A major benefit to CBD is that it doesn’t contain THC, which is the compound that makes users high, so this makes CBD an ideal product for children. Below you will find a step by step outline of how cbd oil is made.
CBD extract oil from cannabis or hemp.
There are many ways to extract the oil from the plant and make cbd oil. Apeks CO2 extraction systems use CO2 as a solvent to extract the oil. The solvent is considered a cleaner, purer form of extraction because there is no residue after extraction.
To isolate the individual compounds (CBD being one of them), the extracted oil needs to be distilled after extraction. The first step is a process called Winterization, followed by Short Path Distillation.
Winterization is the process to remove undesirable elements that were extracted from the plant, for example fats, waxes, and lipids. This process is only needed when the oil was extracted at high pressure/high temperature (supercritical) because this intense extraction pulls everything from the plant, including material you don’t want in the final products. The extracted oil is effectively crude oil, which needs refining.
Once extracted, the mixture is combined with 200 proof alcohol and stirred vigorously until completely mixed. It’s then placed in a deep freezer overnight. In the morning, the mixture looks cloudy and is ready for filtration. One way to filter out the fats, etc. is to run it through a filter paper into an extraction jar. A common piece of equipment for this is a Buchner Funnel. Once it’s been filtered to satisfaction and the undesirable elements have been removed, it’s time to remove the alcohol. This is done using heat. The extraction is warmed and as its warmed, the alcohol evaporates since the boiling point of alcohol is lower than the oil. The removed alcohol may then be used on a different batch of crude oil.
Mixing oil and alcohol prior to freezing
Short Path Distillation equipment
Short Path Distillation
To further refine the CBD extract, and to isolate the CBD, the oil goes through Short Path Distillation. This works in much the same way as Winterization in that the extract is heated and each compound is then separated because each one has a different boiling point. In this way, each compound is isolated and can be used by itself.
Benefits and Uses of CBD
Research is showing that CBD extract has a huge potential in the medical market. CBD’s common benefits are treating anxiety, reducing pain and inflammation, helping prevent seizures, among many others. Because it’s a natural extract, there are few, if any, side effects. The extract works with the body’s endocannabinoid system, which is the system’s method of regulating processes, like pain, mood, appetite, and memory. CBD works with the natural system rather than being an unnatural substance, so the body doesn’t try to reject it. CBD extract may be sourced from cannabis or hemp, most typically from hemp, which is naturally high in CBD. Cannabis can also be bred to have low THC levels and high CBD levels, but it’s possible that the THC will get concentrated and included in your final products.
Tne Entourage Effect
Despite the benefits of CBD as an isolate, there is much to be said for treating patients with all the compounds in the plant, not as separate isolates. Patients can still use the oil without getting high, as long as the THCa has not been heated, which converts it into THC, which is what makes you high. The Entourage Effect is the effect that all the compounds of the plant have on the body, as a whole.
Hemp and cannabis oil extraction processes and techniques.
Andy is on a panel of experts, answering questions from the community. We compiled a collection of questions and answers below, about hemp and cannabis oil extraction processes and techniques.
Click here to get more information on the CBD Extraction Process.
What are the safest and most effective ways to extract and produce CBD-rich cannabis oil? CO2, oil, or ethanol?
What are the safest and the most effective ways to extract and produce CBD oil? CO2, oil, or ethanol?
Thanks for the great question! There are really 2 questions here, so I’ll try to answer them separately.
First question: What are the safest ways to extract? When it comes to extraction, safety is an important issue and has many areas to consider. The list below represents some of the major areas that need to be addressed with the popular solvents being used in the cannabis industry today:
- Materials of Construction- Stainless steel materials for food/consumed oil applications
- Electrical for Flammable Solvents – Class 1, Division 1 (explosion proof) electrical components for compressed flammable gasses, Class 1, Division 2 for ethanol/alcohol
- Electrical, Non Flammable Solvents – NEMA 4x wash down electrical enclosures
- Pressure Rating – usually 300 psi for hydrocarbons, 2000 or 5000psi for CO2.
- Overpressure Protection – non-isolable relief valves set to 110% of maximum allowable working pressure
- Food grade – welds in contact with extracted material should be ground flush and polished
- Accessibility for Cleaning – vessels and piping should be accessible from both ends to allow proper cleaning
- Storage tanks – should be stainless steel to prevent corrosion
Facility – In addition to the equipment considerations, the facility must also be appropriate for the extraction solvent.
- Compressed Flammable Gasses – Class 1, Division 1 facility. This includes electrical fixtures, and also monitoring and evacuation equipment in the event there is a release of flammable gas into the area around the equipment.
- Ethanol/Alcohol – vent hood or equivalent walk in vent area
- CO2 – asphyxiation hazard. Monitoring and audible alarm to warn of leaks.
- CO2 – Generally Regarded as Safe (GRAS) by the FDA for consumption
- Compressed gas – GRAS for use as a propellant, states differ on safe residual solvent levels
- Ethanol – GRAS for food products, states differ on safe residual solvent levels
So the answer to the question about safety really doesn’t have anything to do with the solvent, rather the equipment chosen and the facility where the extraction is performed determine safety. The solvents commonly used in extractions today all have pros and cons, and all can be operated safely as long as proper guidelines and regulations are followed.
I addressed the safety question in the first part of the answer, in the second part I’ll address the efficiency question: What is the most effective way to extract CBD-rich oil?
A major problem facing the cannabis industry today is a lack of commonly accepted standards – as evidenced by the question referring to “CBD-rich”. Does “CBD-rich” mean 40% CBD? 99% CBD? And CBD in what form, CBD, CBD-A or some combination? There are groups that are working towards creating standards, such as FOCUS and ASTM, but they have not been widely accepted yet. Without standards, quality also becomes difficult to determine because the only standard is personal subjectivity.
That being said, there are some generalizations about extraction methods that can be made. Keep in mind – every extraction method has benefits and drawbacks. Each method will shine in certain applications, and perform poorly in other. No method is great at everything.
CBD Oil: A How-To Guide for At-Home Extractions
British pharmaceutical company GW Pharmaceuticals recently received FDA approval of their oral solution Epidolex for treating seizures associated with Tuberous Sclerosis, adding another condition to the list of health issues that their CBD oil solution can successfully and safely treat. Individual users, however, claim that cannabis oil helps reduce pain and anxiety, as well as other issues that still await clinical confirmation.
Apart from its medicinal use, CBD oil can also be used to cook various dishes, sauces, dressings, and gummies. The wave of legalization that has swept North America recently also allowed entrepreneurs to start-up businesses and sell oil and other products made via CBD extraction to a wide array of consumers, not only those with medicinal needs.
If you’re looking for a way to make your own oil, however, this article is here to show you how to extract CBD from a cannabis plant at home.
Distinct types of CBD oil
Depending on the strain you use and the preparation method, there are three different types of CBD oil:
- Full Spectrum
- Broad Spectrum
- CBD Isolate
Each of these three types of products provides a separate set of compounds and effects. It’s very important to know what you’re introducing into your system, especially when it comes to potentially psychoactive substances.
Full Spectrum CBD oil contains more than just CBD; there’s a wide array of other cannabinoids, including THC, terpenes, and essential oils. This type of CBD oil allows the use of both leaves and flowers to assure the presence of every compound; however, leaves hold a high concentration of chlorophyll, which gives the oil a dark color and a somewhat bad taste.
Broad Spectrum CBD oil gives you the full set of substances, as well, however, there is no THC, which means you won’t get high or show positive on a drug test if you consume the oil on a regular basis.
CBD Isolate is the purest form of CBD oil extracted from nothing but the plant flower. If you’re opting for this type of oil, you should use hemp flower for this purpose. Hemp has been legal in the U.S. since the passage of the 2018 Farm Bill.
Since the extraction of Full Spectrum CBD oil is the way to obtain the most of the plant’s benefits to our wellbeing, we’ll go through to examine this method, not only because buying complex equipment for marijuana processing might get you in trouble, but also because it’s the simplest process and easy to implement at home. For those of you who would like to know other methods of marijuana oil extraction, we’ll also mention some alternatives at the end.
Extracting CBD oil from a flower
Before you start the process, it’s of paramount importance to know that Ethanol or Ethyl Alcohol is a highly flammable substance so make sure you take every precaution to keep yourself and your environment safe from fire hazard. That being said, let’s get on with the preparation process.
What do you need?
Cannabis flowers – make sure you trim down every leaf and leave nothing but the flower for the extraction process. Break larger buds into smaller pieces to make it easier for processing or even better, grind the flower so that the herb could absorb the alcohol better.
Ethanol – Best use 95% Food-Grade Ethyl alcohol.
Filtering equipment – Best use paper filters or fold gauze into several layers.
Fireproof bowl – the size of the bowl depends on how much material you have prepared.
Large glass jar – This is where you’ll mix alcohol and weed.
To activate cannabinoids, we must place the ground herb into an oven for about 45 minutes. Spread marijuana over a casserole dish or something similar and keep the oven heated at around 110 degrees Celsius. Depending on the granulation, it could take less than 45 minutes for the decarboxylation process, so pay attention not to burn your weed in the oven.
Mixing and filtering
Place your weed into the jar and pour alcohol over it until it covers the weed completely. Stir the mixture every 5 minutes several times and let the mix sit for an hour or two. You can’t let it sit for too long, so don’t worry if you leave it sitting longer than this.
Place the layered gauze or paper filter over the fireproof bowl and start pouring the solution. It’s not a bad idea to repeat the filtering process several times until you’re satisfied with the achieved purity of the filtered solution.
Removing the alcohol
Ethyl alcohol boils at 78 degrees Celsius which is the temperature you should set on your heating surface and slowly mix the solution within the fireproof bowl. Keep the bowl over the heat source until no alcohol vapor or bubbles is appearing on the surface of the heated liquid.
More oil extraction methods
There are numerous ways to extract oil, some even answer the question of how to extract THC from your product. As these require a bit more experience, we’ll only go through some of the most popular methods.
This is one of the newest ways to produce CBD oil and it offers the purest oil extract, called CBD Isolate, free of any additional compounds. It requires a CO2 machine because it relies on carbon dioxide as a solvent. The herb is being placed into a Co2 machine and kept under pressure. This process also includes the Winterization and Decarboxylation process. The first is used to separate CBD from wax and lipids that might be left, while Decarboxylation activates the CBD.
Similar to Ethanol extraction, the oil method requires the use of olive or coconut oil as a solvent. One major difference is that the herb is being mixed with water and dehydrated before it’s mixed with the oil and heated. This method is most commonly used by people who need to create CBD tinctures or topicals that can be applied directly to the affected area and deal with muscle pain.
We hope this article has helped you capture the basics of CBD oil extraction. We tried to cover the extraction process as comprehensively as possible so you wouldn’t have any setbacks while trying to make your extract at home. Also, we avoided the use of specialized chemistry equipment because, let’s face it, not too many people have a lab set up in the house. Enjoy your new knowledge and have fun making your CBD oil.
Tia is an editor and contributor for AskGrowers. She is passionate about traveling, yoga, and horse-riding, and at some point wants to see every corner of the Earth. She’s been working in the cannabis field for some time and is excited to continue and discover even more about this industry.