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So what’re the differences between CBD, CBDA, CBGA and marijuana plants you’d buy at a dispensary? Wondering about the difference between CBD vs CBDA? We’ve got the answers you’re looking for in this simple guide so you can safely use them.

Cannabis and COVID: Key differences between CBD, CBDA and CBGA

New study finds cannabis compounds block coronavirus proteins

Ken Haddad , Digital Content Manager

GRANTHAM, ENGLAND – AUGUST 27: Hemp oil is tested for quality in the process department at British CBD oil producer Crop England on August 27, 2021 in Grantham, England. British CBD oil was founded in 2019 by Mike and Jackie Lamyman. The popularity of CBD oil from the cannabis family of plants has grown in recent years due to its health properties. (Chris Furlong, 2021 Getty Images)

A study published this week by researchers at Oregon State University found some hemp compounds have the ability to prevent the virus that causes COVID-19 from entering human cells.

Findings of the study led by Richard van Breemen, a researcher with Oregon State’s Global Hemp Innovation Center, College of Pharmacy and Linus Pauling Institute, were published this week in the Journal of Natural Products.

Hemp, known scientifically as cannabis sativa, is a source of fiber, food and animal feed, and multiple hemp extracts and compounds are added to cosmetics, body lotions, dietary supplements and food, van Breemen said.

“We identified several cannabinoid ligands and ranked them by affinity to the spike protein,” van Breemen said. “The two cannabinoids with the highest affinities for the spike protein were CBDA and CBGA, and they were confirmed to block infection.”

So what’re the differences between CBD, CBDA, CBGA and marijuana plants you’d buy at a dispensary?

CBD, an abbreviation for cannabidiol, doesn’t produce any psychoactive effects. It’s likely what you see at some pharmacies, health stores or dispensaries.

It’s a very versatile compound, which makes it ideal for oils, gummies, lotions, creams and other products. Hemp contains a lot of CBD.

But CBD is not the compound that was tested in the Oregon State study. CBD is activated in hemp plants from its original form — CBDA.

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CBDA, known as cannabidiolic acid, is secreted in the stems, leaves and flowers of a cannabis plant. When the plant undergoes activation (a process with heat), the acid is removed from the CBDA, activating CBD.

They have similar compounds, but CBDA is not as versatile. It’s usually extracted by “juicing” plant material, and can be added to foods, drinks, or used in tinctures, concentrated herbal extracts.

But basically, CBDA is the raw form of CBD. And it’s not as easy to find. But you can buy it. (It has not been studied as much as CBD)

CBGA, known as cannabigerolic acid, is considered the “mother cannabinoid,” because without it, there is no CBD, CBDA or THC.

CBGA compounds are similar to other cannabinoids, but it hasn’t been studied nearly as much as the others. It’s non-intoxicating. Enzymes called synthases are responsible for converting the CBGA into molecules such as THCA, the raw, unactivated molecule that converts to THC after heat is applied.

Again, you can find this in oils and tinctures online, but it’s harder to find and at times, pretty expensive, because it’s harder to extract.

What about smoking marijuana?

At this point, it doesn’t appear that just smoking marijuana, even a heavy CBD strain, will produce the effects reported in this study. We don’t have enough information to suggest it.

CBDA or CBGA products, like oils, offering these in their raw form, do not work the same in marijuana products, which usually include high levels of THC, the psychoactive compound that makes you high.

And before trying something new, do your research, talk to your doctor and make sure it’s something you should bring into your life. Check out Project CBD for some information on getting started.

Copyright 2022 by WDIV ClickOnDetroit – All rights reserved.

About the Author:
Ken Haddad

Ken Haddad is the digital content and audience manager for WDIV / ClickOnDetroit.com. He also authors the Morning Report Newsletter and various other newsletters. He’s been with WDIV since 2013. He enjoys suffering through Lions games on Sundays in the fall.

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The Difference Between CBD vs CBDA

While the cannabis plant contains over 100 different cannabinoids, THC and CBD tend to be the ones most commonly talked about. But there are many other cannabinoids that provide unique benefits for the body. One of the lesser-known ones is CBDA or cannabidiolic acid. And while it is similar to CBD, the two have their own unique properties. So what is CBDA, and how is it different from CBD? Here’s a guide on CBDA vs CBD, their effects, and how to use them.

What is CBDA?

Cannabidiolic acid is a type of compound found in cannabis called a cannabinoid. CBD is also a cannabinoid, but you won’t find much CBD if you look at a fresh cannabis plant. Instead, you would see abundant amounts of CBDA. CBDA is a compound that eventually becomes CBD. While CBD comes from grown and cured cannabis plants, CBDA occurs in plants that are still growing. CBDA is what’s known as an acid precursor of CBD and only comes about when raw cannabis containing CBDA is heated, causing what’s known as decarboxylation.

While there has been a lot more scientific research on CBD than CBDA, it is starting to become a cannabinoid of interest. And just like other cannabinoids, CBDA can be used in products for therapeutic use.

How Does CBD Affect the Body?

The medicinal use of CBD is becoming more common every day, and research shows that it is a safe substance with seemingly endless beneficial health effects. Many people use CBD for pain relief. It binds with cannabinoid receptors in the brain and body to reduce inflammation and numb pain. This also makes it great for things like arthritis, injuries, and overall aches and pains. CBD is also popular for boosting mood, reducing anxiety and depression, and getting a good night’s sleep. Research also shows that it can help fight cancer by reducing cancer cells’ growth, and it helps reduce nausea for cancer patients going through chemotherapy.

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How Does CBDA Affect the Body?

We are learning that CBDA also provides positive health effects a lot like CBD. And while the two are closely related, they actually work in different ways. CBDA doesn’t bind to cannabinoid receptors the way that CBD does. But it does interact with the body’s endocannabinoid system and boots serotonin production. Studies show that CBDA can act as a COX-2 inhibitor, making it great for reducing inflammation and pain. It can also work as an antiemetic and help fight feelings of nausea and vomiting. One study even found that it works better than CBD at reducing nausea. It also has antidepressant-like effects, can help with sleep, and be used to treat epilepsy.

CBD and CBDA have many similarities, but since they work in the body differently, CBDA may be better at relieving certain symptoms than CBD. And science is just starting to learn about CBDA’s unique benefits.

CBD vs CBDA: How to Use CBD and CBDA

Both CBD and CBDA can be found in oils, tinctures, topicals, and other easy-to-use products. But some users juice the leaves of fresh cannabis to get the freshest form of cannabidiolic acid. Both CBD and CBDA can provide a lot of similar health benefits, and using them depends on your personal preferences and which one is better at helping your symptoms. The best approach is to use them together. Like other cannabinoids, they work very well when combined and can boost each other’s benefits through what’s known as the entourage effect.

Ready to see what CBD and CBDA can do for you? Come down and see us at one of our dispensary locations and our friendly budtenders will be happy to help you find the products that are right for you!

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