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Prickly Lettuce

Agdex#: 642
Publication Date: 07/03
Order#: 03-041
Last Reviewed: 08/09
History: Original Document
Written by: Susan Weaver/Agriculture and Agri-Food Canada; Michael Downs/Agriculture and Agri-Food Canada

Table of Contents

  1. Description and Life Cycle
  2. Economic Impact
  3. Control
  4. Related Links

Description and Life Cycle

Prickly lettuce is a winter annual weed often found in no-till soybeans and winter wheat, or along field edges. It is sometimes referred to as “wild lettuce”, because it is closely related to, and inter-fertile with, cultivated lettuce. Another common name is “compass plant”, because the leaves on the main stem are held vertically in a north-south plane, perpendicular to direct sunlight. (Figure 1) The French common name for prickly lettuce is “laitue scariole”, which derives from its scientific name, Lactuca serriola or Lactuca scariola.

Figure 1. Juvenile plant with elongating stem in late spring. Notice the deteriorating rosette leaves.

Prickly lettuce forms a rosette of leaves after emergence, usually in autumn, and develops a long taproot. It overwinters as a rosette, and then produces one or more flowering stems in early summer. Each flowering stem bears many small (8-12 mm in diameter) yellow flower heads during July and August. (Figure 2) The small, greyish brown seeds (4-5 mm long) have an attached pappus and are wind-dispersed. The leaves, roots and stems exude a milky juice when damaged.

Figure 2. Prickly lettuce flower heads, located along the stems and branches, are smaller than sow-thistle flowers.

Prickly lettuce may be mistaken for dandelion, at the rosette stage, or for sow-thistles at any stage. All of these species are members of the sunflower family, contain a milky latex, have yellow flowers and produce numerous wind-dispersed seeds. A distinguishing feature of prickly lettuce is a row of spines along the midrib on the underside of the leaf. (Figure 3) These spines are occasionally absent from small, upper stem leaves or from leaves on stems that have regrown after mowing.

Figure 3.Row of spines along midrib on the underside of leaf of prickly lettuce. Sow-thistles have spines along the leaf margins, but not on the midrib.

Prickly lettuce is native to the Mediterranean region, and was introduced to Ontario in the late 1890’s, subsequently spreading by seeds along roadsides, railways and watercourses throughout most of southern Canada. It remained a weed of roadsides and waste ground until the adoption of reduced tillage systems provided an opportunity to thrive in crops. The absence of tillage in the autumn or spring allows this weed to complete its life cycle undisturbed. The wind-dispersed seeds often catch and settle on crop stubble or residue found in no-till fields.

Most emergence occurs in the autumn, beginning in late September and extending into November in the warmer parts of Ontario. A long, warm autumn favours emergence and rosette establishment, and often results in large populations the following year. Some emergence (

Seed production is proportional to plant height. Plants that are 0.5 m tall produce about 35 flower heads, where-as plants that are 1.5 m tall can produce as many as 2,300 flowers. Each flower head contains an average of 20 seeds, giving an estimated seed production of 700 and 46,000 seeds per plant, respectively. Most seeds are viable and ready to germinate immediately after dispersal. Prickly lettuce forms only a short-term seed bank, with seeds surviving 1-3 yr in soil.

Economic Impact

Prickly lettuce is drought tolerant and competes strongly with soybeans for water in a dry season, resulting in reduced yield. In winter wheat it can have detrimental effects on crop value and harvesting efficiency. If the plant is in flower at grain harvest, the flower buds can be difficult to screen out of the grain, resulting in discounted prices. The sticky white latex in the stems can clog harvesting equipment and raise the moisture content of the grain. Stem latex is less of a problem at soybean harvest, when plants have senesced and stems have dried.

Cattle feeding exclusively on fresh, young prickly lettuce plants have been reported to develop pulmonary emphysema, but mature plants and dried younger plants appear to be non-toxic. Prickly lettuce has been declared a noxious weed in Manitoba, but not in any other province.


Seedlings and rosettes of prickly lettuce are easily controlled by cultivation, and it is not usually found in tilled fields. Mowing of rosettes is not an effective control practice, because leaves lie close to the soil surface. Plants that are mown after stem extension readily produce new stems or branches and flowers.

Rosettes of prickly lettuce can be controlled in the fall or spring by non-selective herbicides containing glyphosate, glufosinate ammonium, or paraquat, with larger rosettes requiring higher rates. Plants are difficult to control with herbicides once the flowering stems have begun to elongate. Preemergence applications of products containing atrazine, metribuzin, napropamide, chlorsulfuron, isoxaben, oxyfluorfen, oxadiazon or terbacil will usually control germinating seedlings. Postemergence applications of 2,4-D, MCPA, dicamba, clopyralid, bromoxynil plus atrazine, metribuzin, linuron with oil, or thifensulfuron-methyl/tribenuron-methyl, can control prickly lettuce rosettes in a variety of crops. Postemergence application of products containing cloransulam-methyl or chlorimuron-ethyl in soybeans provide suppression but not complete control. Consult the latest edition of OMAF Publication 75, Guide to Weed Control, for trade names, crop registrations and rates of these products.

Prickly lettuce has acquired resistance to Group II herbicides in the northwestern United States and Australia. Although herbicide resistance in this species has not yet been found in Canada, rotation of herbicide groups and crops is recommended to prevent the development and spread of resistant plants.

Prickly lettuce is a winter annual weed often found in no-till soybeans and winter wheat, or along field edges. It is sometimes referred to as "wild lettuce", because it is closely related to, and inter-fertile with, cultivated lettuce.


Acrid Lettuce, Bitter Lettuce, German Lactucarium, Green Endive, Lactuca virosa, Lactucarium, Laitue Amère, Laitue à Opium, Laitue Sauvage, Laitue Scariole, Laitue Serriole, Laitue Vireuse, Lechuga Silvestre, Lettuce Opium, Poison Lettuce, Strong-Scented Lettuce.

  • Overview
  • Uses
  • Side Effects
  • Interactions
  • Dosing

Overview Information

Wild lettuce is a plant. The leaves, sap (latex), and seed are used to make medicine.

Wild lettuce is used for whooping cough, asthma, urinary tract problems, cough, trouble sleeping (insomnia), restlessness, excitability in children, painful menstrual periods, excessive sex drive in women (nymphomania), muscular or joint pains, poor circulation, swollen genitals in men (priapism), and as an opium substitute in cough preparations.

The seed oil is used for “hardening of the arteries” (atherosclerosis) and as a substitute for wheat germ oil.

Some people apply wild lettuce latex directly to the skin to kill germs.

Some people inhale wild lettuce for a recreational “high” or hallucinogenic effect.

How does it work?

Wild lettuce has calming, relaxing, and pain relieving effects.

Uses & Effectiveness ?

Insufficient Evidence for

  • Whooping cough.
  • Asthma.
  • Urinary tract problems.
  • Cough.
  • “Hardening of the arteries” (atherosclerosis).
  • Trouble sleeping (insomnia).
  • Restlessness.
  • Painful menstrual periods.
  • Sexual disorders.
  • Muscle and joint pain.
  • Killing germs, when the latex is applied to the skin.
  • Other conditions.

More evidence is needed to rate the effectiveness of wild lettuce for these uses.

Side Effects & Safety

Wild lettuce is POSSIBLY SAFE for most people in small amounts.

Wild lettuce is LIKELY UNSAFE when eaten in large amounts or when the wild lettuce has been harvested too early. This can cause sweating, fast heartbeat, pupil dilation, dizziness, ringing in the ears, vision changes, sedation, breathing difficulty, and death.

Applying wild lettuce directly to the skin can cause irritation.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of wild lettuce during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Enlarged prostate (benign prostatic hyperplasia, BPH): Don’t use wild lettuce if you have this condition. It contains a chemical that can harm people who have trouble urinating.

Allergy to ragweed and related plants: Wild lettuce may cause an allergic reaction in people who are sensitive to the Asteraceae/Compositae family. Members of this family include ragweed, chrysanthemums, marigolds, daisies, and many others. If you have allergies, be sure to check with your healthcare provider before taking wild lettuce.

Narrow-angle glaucoma: Don’t use wild lettuce if you have this eye condition. It contains a chemical that might make glaucoma worse.

Surgery: Wild lettuce can affect the central nervous system. There is a concern that it might cause too much sleepiness if it is taken along with anesthesia and other nerve-numbing medications used during and after surgery. Stop using wild lettuce at least 2 weeks before a scheduled surgery.

Learn more about Wild Lettuce uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain Wild Lettuce